Melatonin Reduces Free Radical Production in Exercise

by Dr. Jason Barker July 12, 2011

Melatonin Reduces Free Radical Production in Exercise

A new study shows that the hormone melatonin significantly decreased the production of free radicals during and after intense exercise. Melatonin is a hormone released from our brains. It is most ‘famous’ as a sleep aid, however it has a lot of other important effects in the body.

Strenuous exercise: causes the release of free radicals and other pro-inflammatory chemicals in the body. These can damage the muscles and organs and contribute to the aging process overall.

Study subjects ran a 50-kilometer race with 2800 meters of climbing and were then evaluated for production of pro-inflammatory chemicals. (These included tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, and IL-1ra, as well as 8-hydroxy-2’-deoxyguanosine, a marker of oxidative stress, and isoprostane, a marker of lipid peroxidation.)

The subjects who took melatonin before their run showed significantly decreased levels of the pro-inflammatory chemicals and had decreased production of oxidative compounds, signifying an overall decrease in free radical production.

This is yet another example of how anti-oxidant compounds, when taken close to exercise, can reduce the body’s natural production of pro-inflammatory and pro-oxidative chemicals.  This is a good thing, as those chemicals are not good for your health or performance!  

Reference:

Ochoa JJ, Díaz-Castro J, Kajarabille N, García C, Guisado IM, De Teresa C, Guisado R. Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males. J Pineal Res. 2011 Apr 21. 

Dr. Jason Barker
Dr. Jason Barker


Leave a comment

Comments will be approved before showing up.


Also in Natural Athlete Solutions

Adaptogenic Herbs To The Rescue
Adaptogenic Herbs To The Rescue

by Dr. Jason Barker February 20, 2018

Adaptogenic herbs help the body increase its resistance to stress, and turn down the body's response to it as well. Here's how adaptogens like Rhodiola can help you with stress, regardless of what kind it is.
Read More
Organizing Yourself to Eat Healthy
Organizing Yourself to Eat Healthy

by Chris Barker February 13, 2018

Disorganization can throw you off your health diet in a hurry.  Here's how we stay organized and on track!
Read More
Fueling for Performance vs Health
Fueling for Performance vs Health

by Dr. Jason Barker February 06, 2018

What's the difference between eating for performance, and eating for health?
Read More
Sign up & receive 10% off your order
Want to save 10% on your order today?