Receive 10% Off

Melatonin Reduces Free Radical Production in Exercise

by Dr. Jason Barker July 12, 2011

Melatonin Reduces Free Radical Production in Exercise

A new study shows that the hormone melatonin significantly decreased the production of free radicals during and after intense exercise. Melatonin is a hormone released from our brains. It is most ‘famous’ as a sleep aid, however it has a lot of other important effects in the body.

Strenuous exercise: causes the release of free radicals and other pro-inflammatory chemicals in the body. These can damage the muscles and organs and contribute to the aging process overall.

Study subjects ran a 50-kilometer race with 2800 meters of climbing and were then evaluated for production of pro-inflammatory chemicals. (These included tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, and IL-1ra, as well as 8-hydroxy-2’-deoxyguanosine, a marker of oxidative stress, and isoprostane, a marker of lipid peroxidation.)

The subjects who took melatonin before their run showed significantly decreased levels of the pro-inflammatory chemicals and had decreased production of oxidative compounds, signifying an overall decrease in free radical production.

This is yet another example of how anti-oxidant compounds, when taken close to exercise, can reduce the body’s natural production of pro-inflammatory and pro-oxidative chemicals.  This is a good thing, as those chemicals are not good for your health or performance!  

Reference:

Ochoa JJ, Díaz-Castro J, Kajarabille N, García C, Guisado IM, De Teresa C, Guisado R. Melatonin supplementation ameliorates oxidative stress and inflammatory signaling induced by strenuous exercise in adult human males. J Pineal Res. 2011 Apr 21. 

Dr. Jason Barker
Dr. Jason Barker


Leave a comment

Comments will be approved before showing up.


Also in Natural Athlete Solutions

The Tastiest, Healthiest Nutritional Green Drink We Have!
The Tastiest, Healthiest Nutritional Green Drink We Have!

by Dr. Jason Barker

Greens First Pro is an innovative phytonutrient and antioxidant blended green drink that contains 49 organic plant extracts and concentrates of fruits, vegetables, herbs, digestive enzymes, probiotics, spices and both soluble and insoluble fiber.   It's simply the best healthy green smoothie blend out there!

Read More
How Do Exercise & Fitness Affect Immunity to Covid-19?
How Do Exercise & Fitness Affect Immunity to Covid-19?

by Dr. Jason Barker

How you exercise has a direct effect on your immunity and plays a role in how you can fight of infections like covid-19. Dr. Barker reviews the right dosage of exercise to boost immunity in this video.
Read More
Preventing Reactive Hypoglycemia with Exercise
Preventing Reactive Hypoglycemia with Exercise

by Dr. Jason Barker 5 Comments

Ever exercise only to ‘bonk’ shortly after starting?  This is probably reactive hypoglycemia, or low blood sugar that can cause symptoms of being dizzy, shaky, sweaty and “hangry” (so hungry you’re angry!)  Here’s how you can prevent that from happening.

Read More