Mountain Peak Nutritionals Joint formula contains the ingredients needed to support cartilage regeneration, minimize the inflammatory response, and reduce pain associated with joint conditions.
Chondroitin sulfate was not included because of its extremely large molecular nature which limits is absorption rate in comparison to glucosamine sulfate, which has a superior bioavailability.In fact, glucosamine is one of the only natural compounds that can actually slow or even stop the progression of cartilage degeneration (osteoarthritis).
Glucosamine sulfate is a necessary ingredient for the production of several joint compounds (known as mucopolysaccharides) that form the framework for several different types of connective tissue throughout the body including synovial fluid, cartilage, tendons, ligaments and others.
Glucosamine is thought to slow and even stop the progression of osteoarthritis; it has a stimulatory effect on chondrocytes (cells that produce cartilage) and the synovial cells (which line the outer layers of cartilage).
Research points to the sulfate aspect of glucosamine as being responsible for this effect in osteoarthritis; sulfate is needed for cartilage synthesis. This is in comparison to the less effective glucosamine hydrochloride.
The glucosamine in Joint formula is derived from marine life exoskeletons (the hard outer shells of crustaceans, primarily) and it contains 1500mg of glucosamine which is the clinically recommended amount for maximum benefit.
Boswellia Serrata (Indian Frankincense) is an Ayurvedic herb found in India and Nepal.It has a long historical use for joint and connective tissue problems. Modern research supports these historical uses as the main constituents of the herb, boswellic acids have been shown to suppress the growth of inflamed tissue in joints, ligaments and tendons.Boswellic acids have powerful anti-inflammatory effects and can inhibit 5-lipoxygenase and leukotrienes, two of the body’s primary inflammatory molecules.
Devil’s Claw is a botanical medicine with potent inhibitory effects on the pro-inflammatory cyclooxygenase (COX) and lipoxygenase inflammatory pathways.
Curcumin is a compound derived from Turmeric, a common spice. Curcumin and its related compounds inhibit a number of pro-inflammatory compounds (cyclooxygenase-2 (COX-2) prostaglandins, and leukotrienes).Normally, curcumin is very weakly absorbed by the body, however Joint formula contains Meriva® which is 20 times better absorbed than standard turmeric extract.
Bromelain is an enzyme derived primarily from the stems (and to a lesser extent the fruit) of pineapple.It inhibits two pro-inflammatory compounds in the body - kinins and fibrin. Bromelain has also been shown to minimize the pain and inflammation associated with sports injuries and joint pain.
Ginger root has widespread pharmacological effects including fever reducing, pain relieving, ant-cough, anti-inflammatory, sedative and other properties.The main active compounds of ginger (gingerol and shogaol) have been shown to inhibit the cyclooxygenase (COX) and lipoxygenase inflammatory pathways.
Vitamin C is required for the production of hydroxyproline, one of the main building blocks of collagen (which is the main compound in joints and other connective tissues).Vitamin C has been shown to boost collagen and proteoglycan (another joint chemical) production. Additionally, oxidative stress is one of the reasons joint tissue degenerates; vitamin C reduces oxidative stress and in one study, patients with osteoarthritis that had a high vitamin C intake had reduced risk of cartilage degeneration and disease progression.
Manganese serves as a cofactor in the production and maintenance of bone and connective tissue, and is found in high concentrations in synovial fluid.
Zinc and Copper -are both highly important enzymatic cofactors throughout the body. People with rheumatoid arthritis have been shown to deficiency in both zinc and copper.One of the body’s main antioxidant enzymes (super oxide dismutase) relies heavily on zinc and copper to combat inflammation throughout the body.
If you’re a runner, walker or hiker, or really anyone who depends heavily on healthy joint function (which is all of us), Joint formula will not only protect your joints from degeneration but it can also effectively ease the pain and discomfort that may be holding you back from doing what you want to do!